Cambridge, MA, and Oxford, U.K., with primary manufacturing facilities in Speke, Liverpool, U.K.; Novartis AG acquired Chiron and its vaccine subsidiariies in late 2005; formerly Chiron Vaccines, a subsidiary of Chiron Corp.; also vaccine manufacturing facilities in Sienna, Italy (Chiron S.p.A.); Marburg, Germany, facility is CBER/FDA est. no. 1751
